Overview
- Product nameAnti-UXS-1 antibodySee all UXS-1 primary antibodies ...
- DescriptionRabbit polyclonal to UXS-1
- Tested applicationsIHC-P, WB more details
- Species reactivityReacts with: Human
- Immunogen
amino acids 40-145 of Human UXS-1.
- Positive controlHuman cerebral cortex tissue, transfected HEK293T cells overexpressing UXS-1 with a C-terminal myc-DDK tag.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab121291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| IHC-P | IHC-P: 1/10. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
| WB | WB: 1/250 - 1/500. Detects a band of approximately 55-72 kDa (predicted molecular weight: 51 kDa). |
Target
- FunctionCatalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
- PathwayNucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.
- Sequence similaritiesBelongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily.
- Cellular localizationGolgi apparatus > Golgi stack membrane.
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Database links
- Entrez Gene: 80146 Human
- Entrez Gene: 80146 Human
- Omim: 609749 Human
- SwissProt: Q8NBZ7 Human
- SwissProt: Q8NBZ7 Human
- Unigene: 469561 Human
Target information above from: UniProt accession
Q8NBZ7
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- FLJ23591 antibodySDR6E1 antibodyshort chain dehydrogenase/reductase family 6E, member 12 antibody
- UDP-glucuronate decarboxylase 1 antibodyUDP-glucuronic acid decarboxylase 1 antibodyUGD antibodyUXS-1 antibodyuxs1 antibodyUXS1_HUMAN antibody
see all
Anti-UXS-1 antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UXS-1 antibody (ab121291)ab121291, at a 1/10 dilution, staining UXS-1 in neuronal cells of paraffin-embedded Human cerebral cortex tissue by immunohistochemistry. -
Western blot - Anti-UXS-1 antibody (ab121291)All lanes : Anti-UXS-1 antibody (ab121291) at 1/250 dilution
Lane 1 : Vector only transfected HEK293T cell lysate
Lane 2 : Lysate from transfected HEK293T cells overexpressing UXS-1 with a C-terminal myc-DDK tag (~3.1 kDa)
Predicted band size : 51 kDa -
Western blot - Anti-UXS-1 antibody (ab121291)
Predicted band size : 51 kDa
References for Anti-UXS-1 antibody (ab121291)
ab121291 has not yet been referenced specifically in any publications.
