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Products:Cell Biology >> Proteolysis / Ubiquitin >> Proteasome / Ubiquitin >> Ubiquitin E2s and E3s >> Ubiquitin E2 Enzymes
Overview
Product name
Ube2L6 protein (His tag)
Protein description
Recombinant full length (aa 1-152) human Ube2L6 protein, fused to His tag at N terminus; 188 amino acids, 21.7kDa. Swiss ID = O14933.
Expression host
E. coli
Properties
Purity
>90% by SDS-PAGE
Purification notes
ab79192 is purified using conventional chromatography techniques.
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 10% Glycerol, 20mM Tris, 1mM DTT, 0.1mM PMSF, pH 8.0
Concentration
Concentration information loading...
Sequence notes
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASM RVVKELEDLQ KKPPPYLRNL SSDDANVLVW HALLLPDQPP YHLKAFNLRI SFPPEYPFKP PMIKFTTKIY HPNVDENGQI CLPIISSENW KPCTKTCQVL EALNVLVNRP NIREPLRMDL ADLLTQNPEL FRKNAEEFTL RFGVDRPS
Research areas
Epigenetics and Nuclear Signaling >> Ubiquitin & Ubiquitin Like Modifiers >> Ubiquitin like Modifiers
Epigenetics and Nuclear Signaling >> Ubiquitin & Ubiquitin Like Modifiers >> E2 Ubiquitin Conjugating Enzymes
Cell Biology >> Proteolysis / Ubiquitin >> Proteasome / Ubiquitin >> Ubiquitin E2s and E3s >> Ubiquitin E2 Enzymes
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SDS-PAGE - Ube2L6 protein (His tag) (ab79192)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab79192 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
Protein info
Function
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
Tissue specificity
Present in natural killer cells (at protein level).
Pathway
Protein modification; protein ubiquitination.
Sequence similarities
Belongs to the ubiquitin-conjugating enzyme family.
Post-translational
modifications
ISGylated.
Target information above from: UniProt accessionO14933
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Ube2L6 protein (His tag) images:
SDS-PAGE - Ube2L6 protein (His tag) (ab79192)
15% SDS-PAGE showing ab79192 at approximately 22kDa (3µg).
References for Ube2L6 protein (His tag) (ab79192)
ab79192 has not yet been referenced specifically in any publications.
Publishing research using ab79192? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"