You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252)

MSCatalog No. MS303

CodeSizePriceAbpointsAvailability
    
Add to basket
 

  • -

  •   
  •   
  •   

  •  

  •  
  •  

  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Overview

Product name

Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5]
See all Ubiquinol-Cytochrome C Reductase Core Protein I products (4) ...

Description

Mouse monoclonal [16D10AD9AH5] to Ubiquinol-Cytochrome C Reductase Core Protein I

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Cow, Human

Immunogen

Bovine Ubiquinol-Cytochrome C Reductase Core Protein I protein.

Positive control

Human, Cow, Rat or Mouse heart mitochondrial lysate, HepG2 mitochondrial lysate.

Properties

Form

Liquid

Storage instructions

Store at +4°C. Do not freeze.

Storage buffer

Preservative: 0.02% Sodium azide
Constituent: HBS

Concentration

Concentration information loading...

Purity

IgG fraction

Purification notes

ab110252 is produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.

Clonality

Monoclonal

Clone number

16D10AD9AH5

Isotype

IgG1

Light chain type

kappa

Research areas

Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Cytochromes
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Oxidative phosphorylation >> Complex III
Metabolism >> Pathways and Processes >> Redox metabolism >> Antioxidants
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Mitochondrial markers
Signal Transduction >> Metabolism >> Mitochondrial
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Mitochondria

  • Western blot - Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252)Western blot - Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab110252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.

Sequence similarities

Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.

Cellular localization

Mitochondrion inner membrane.

Target information above from: UniProt accessionP31930 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • mitochondrial antibody
  • Complex III subunit 1 antibody
  • Core protein I antibody
  • Cytochrome b c1 complex subunit 1, mitochondrial antibody
  • Cytochrome b-c1 complex subunit 1 antibody
  • D3S3191 antibody
  • OTTHUMP00000164820 antibody
  • QCR1 antibody
  • QCR1_HUMAN antibody
  • Ubiquinol cytochrome c reductase core protein I antibody
  • Ubiquinol-cytochrome-c reductase complex core protein 1 antibody
  • UQCR1 antibody
  • Uqcrc1 antibody
see all

Database links

see all

Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] images:

  Western blot - Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252)

Western blot - Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252)

All lanes : Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252) at 0.5 µg/ml

Lane 1 : Human heart mitochondrial lysate
Lane 2 : Cow heart mitochondrial lysate
Lane 3 : Rat heart mitochondrial lysate
Lane 4 : Mouse heart mitochondrial lysate
Lane 5 : HepG2 mitochondrial lysate


Predicted band size : 53 kDa


Extra bands in the Mouse sample (lane 4) are due to the reaction of the IgG-specific goat anti-mouse secondary antibody with residual mouse blood in the heart tissue, as it is very difficult to entirely remove the blood from these small organs.

References for Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody [16D10AD9AH5] (ab110252)

This product has been referenced in:

  • Son M  et al. Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo. Neurobiol Dis 34:155-62 (2009).Read more (PubMed: 19320055) »
  • Hu Y  et al. Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem 284:547-55 (2009).Read more (PubMed: 19004814) »

See all 16 publications for this product

Publishing research using ab110252? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"