Recombinant Anti-Uridine Phosphorylase 1 antibody [EPR7680] (ab128854)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7680] to Uridine Phosphorylase 1
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-Uridine Phosphorylase 1 antibody [EPR7680]
See all Uridine Phosphorylase 1 primary antibodies -
Description
Rabbit monoclonal [EPR7680] to Uridine Phosphorylase 1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human Uridine Phosphorylase 1. The exact sequence is proprietary.
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Positive control
- 293T cell lysate; HeLa cell lysate; HCT116 cell lysate; Human fetal kidney tissue lysate
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Dissociation constant (KD)
KD = 5.30 x 10 -11 M Learn more about KD -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR7680 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab128854 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/1000 - 1/10000. Detects a band of approximately 31 kDa (predicted molecular weight: 34 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 31 kDa (predicted molecular weight: 34 kDa). |
Target
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Function
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. -
Pathway
Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1. -
Sequence similarities
Belongs to the PNP/UDP phosphorylase family. - Information by UniProt
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Database links
- Entrez Gene: 7378 Human
- Omim: 191730 Human
- SwissProt: Q16831 Human
- Unigene: 488240 Human
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Alternative names
- UDRPASE antibody
- UP antibody
- UPase 1 antibody
see all
Images
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All lanes : Anti-Uridine Phosphorylase 1 antibody [EPR7680] (ab128854) at 1/1000 dilution
Lane 1 : 293T cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : HCT116 cell lysate
Lane 4 : Human fetal kidney tissue lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 34 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab128854 has been referenced in 1 publication.
- Wang X et al. UPP1 Promotes Lung Adenocarcinoma Progression through Epigenetic Regulation of Glycolysis. Aging Dis 13:1488-1503 (2022). PubMed: 36186123