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Overview

  • Product nameUrokinase protein (Active)See all Urokinase proteins and peptides ...
  • Protein descriptionRecombinant full length protein: MKVWLASLFL CALVVKNSEG GSVLGAPDES NCGCQNGGVC VSYKYFSRIR RCSCPRKFQG EHCEIDASKT CYHGNGDSYR GKANTDTKGR PCLAWNAPAV LQKPYNAHRP DAISLGLGKH NYCRNPDNQK RPWCYVQIGL RQFVQECMVH DCSLSKKPSS SVDQQGFQCG QKALRPRFKI VGGEFTEVEN QPWFAAIYQK , corresponding to amino acids 1-433 of Mouse Urokinase
  • Expression hostInsect cells

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab92641 is > 98% pure by SDS-PAGE.
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 0.1M Sodium chloride, 0.05M Sodium acetate, 1mM EDTA, pH 5.0
  • Concentration information loading...
  • Additional notesSpectrophotometric Data: Ultraviolet: Absorbance (280nm) = 0.9 epsilon 0.1% = 1.36
  • SequenceMKVWLASLFLCALVVKNSEGGSVLGAPDESNCGCQNGGVC VSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYR GKANTDTKGRPCLAWNAPAVLQKPYNAHRPDAISLGLGKH NYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCSLSKKPSS SVDQQGFQCGQKALRPRFKIVGGEFTEVENQPWFAAIYQK
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab92641 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies
    ELISA
    SDS-PAGE
  • Application notesELISA: Use at an assay dependent dilution.
    FuncS: Use at an assay dependent dilution.
    SDS-PAGE: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        ATFATF uPABDPLT5
        OTTHUMP00000019849Plasminogen activatorPlasminogen activator urinaryPlasminogen activator urokinasePLAUQPDu PAU plasminogen activatoru-PAU-plasminogen activatorUPAURKUROK_HUMANUrokinase plasminogen activatorUrokinase type plasminogen activatorUrokinase type plasminogen activator precursorUrokinase-type plasminogen activator chain B
      see all
  • FunctionSpecifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • Tissue specificityExpressed in the prostate gland and prostate cancers.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications    Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P00749 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Urokinase protein (Active) images

    • SDS-PAGE - Urokinase protein (Active) (ab92641)
      SDS-PAGE - Urokinase protein (Active) (ab92641)
      12% SDS-PAGE
      Lane 1: Urokinase (5 ug) Reduced
      Lane 2: Urokinase + CPAI (20 ug) Reduced
      Lane 3: Urokinase (5 ug) Non-reduced
      Lane 4: Urokinase + CPAI (20 ug) Non-reduced
      Lane 5: Prestained Standard

    References for Urokinase protein (Active) (ab92641)

    ab92641 has not yet been referenced specifically in any publications.

    Publishing research using ab92641 ? Please let us know so that we can cite the reference in this datasheet

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