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Product name
Anti-Uroplakin III antibody, prediluted
See all Uroplakin III products (6) ...
Description
Rabbit polyclonal to Uroplakin III, prediluted
Tested applications
IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
A synthetic peptide corresponding to C-terminus of human uroplakin III.
Epitope
C-terminus
Positive control
Human Bladder
Properties
Form
Prediluted
Storage instructions
Store at +4°C. Do not freeze.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Applications
Show applications key
Our Abpromise guarantee covers the use of ab82172 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
IHC-P
Application notes
IHC-P: Ready to use.
Boil tissue section in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
Tissue specificity
Expressed in ureter.
Involvement in disease
Defects in UPK3A are a cause of renal adysplasia (RADYS) [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.
Sequence similarities
Belongs to the uroplakin-3 family.
Cellular localization
Endoplasmic reticulum membrane. Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
Target information above from: UniProt accessionO75631
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- MGC119178 antibody
- OTTHUMP00000028951 antibody
- UP III antibody
see all
Database links
- Entrez Gene: 7380 Human
- Omim: 611559 Human
- SwissProt: Q32N05 Human
- SwissProt: O75631 Human
- Unigene: 632787 Human
Anti-Uroplakin III antibody, prediluted images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Uroplakin III antibody, prediluted (ab82172)
Formalin-fixed, paraffin-embedded section of Human bladder stained with ab82172 (ready to use). Incubate primary antibody (ab82172) for 10 minutes at RT.
Western blot - Uroplakin III antibody, prediluted (ab82172)
Anti-Uroplakin III antibody, prediluted (ab82172) at 1/100 dilution + lysate prepared from bladder
Image produced using the diluted version of this antibody, ab82173.
References for Anti-Uroplakin III antibody, prediluted (ab82172)
ab82172 has not yet been referenced specifically in any publications.
Publishing research using ab82172? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"