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Anti-VAMP2 antibody [SP10] (ab90433)

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Overview

Product name

Anti-VAMP2 antibody [SP10]
See all VAMP2 products (9) ...

Description

Mouse monoclonal [SP10] to VAMP2

Specificity

This antibody is reactive with VAMP1 (amino acids 1-118) and the VAMP2 (amino acids 33-96)-proprietary tagged fusion proteins expressed in E. coli. No reactivity was seen with a ~18 kDa protein in mouse liver extracts.

Tested applications

WB, IHC-Pmore details

Cross reactivity

Reacts with

Mouse, Rat, Sheep, Rabbit, Guinea pig, Hamster, Cow, Human, Pig, Xenopus laevis, Monkey

Immunogen

Fractions containing synaptic vesicles (Immunoprecipitated from Human brain homogenates using anti-human Synaptophysin monoclonal antibodies)

Positive control

Rat brain tissue extract

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 50% Glycerol, PBS, 0.1mM PMSF, pH 7.2

Concentration

Concentration information loading...

Purity

Ammonium Sulphate Precipitation

Clonality

Monoclonal

Clone number

SP10

Isotype

IgM

Research areas

Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Energy transfer pathways >> Integration of energy
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> SNAPs & SNAREs

Applications

Show applications key

Our Abpromise guarantee covers the use of ab90433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Involved in the targeting and/or fusion of transport vesicles to their target membrane.

Tissue specificity

Nervous system and skeletal muscle.

Sequence similarities

Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.

Cellular localization

Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome. Neuronal synaptic vesicles.

Target information above from: UniProt accessionP63027 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • FLJ11460 antibody
  • RATVAMPB antibody
  • RATVAMPIR antibody
  • SYB antibody
  • SYB2 antibody
  • Synaptobrevin 2 antibody
  • Synaptobrevin-2 antibody
  • VAMP 2 antibody
  • VAMP-2 antibody
  • Vamp2 antibody
  • VAMP2_HUMAN antibody
  • Vesicle associated membrane protein 2 antibody
  • Vesicle-associated membrane protein 2 (synaptobrevin 2) antibody
  • Vesicle-associated membrane protein 2 antibody
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Database links

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References for Anti-VAMP2 antibody [SP10] (ab90433)

ab90433 has not yet been referenced specifically in any publications.

Publishing research using ab90433? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"