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Western blot - VAMP4 antibody (ab45061)
(enlarge)
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Product Name
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VAMP4 antibody - Vesicle Marker
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See all VAMP4 antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to VAMP4 - Vesicle Marker
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human VAMP4. (Peptide available as ab45264.)
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Cow
(Due to sequence homology)
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 16 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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ab45061 gave a positive signal in the following Human Lysates: Brain, Testis, Liver, Hela and HepG2.
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Cellular localization
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Golgi Apparatus
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Research areas
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Signal Transduction >> Protein Trafficking >> Golgi Proteins
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> SNAPs & SNAREs
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Relevance
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VAMP4 belongs to the synaptobrevin family and contains 1 v-SNARE coiled-coil homology domain. It is involved in the pathway that removes an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. Vamp4 may be a marker for this sorting pathway that is critical for remodeling the secretory response of the secretory granule. It may play a role in trans-Golgi network-to-endosome transport.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.600 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this VAMP4 antibody - Vesicle Marker is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for VAMP4 antibody - Vesicle Marker images, references, products related to ab45061 and other tools.
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VAMP4 antibody - Vesicle Marker images:
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Search PubMed (MEDLINE) for references to VAMP4
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VAMP4 antibody - Vesicle Marker - more information
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VAMP4 antibody - Vesicle Marker - other tools:
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Western blot - VAMP4 antibody (ab45061)