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Anti-VAMP8 antibody (ab81025)

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Overview

Product name

Anti-VAMP8 antibody
See all VAMP8 products (4) ...

Description

Rabbit polyclonal to VAMP8

Specificity

Specific for VAMP8.

Tested applications

WB, IHC-P, IHC-Frmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide (Human) from the internal region of VAMP8.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 1X PBS

Concentration

Concentration information loading...

Purity

IgG fraction

Clonality

Polyclonal

Isotype

IgG

Applications

Show applications key

Our Abpromise guarantee covers the use of ab81025 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 10 - 50 µg/ml.Predicted molecular weight: 11 kDa.(This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.)

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    IHC-P

     IHC-P: Use a concentrati...Read more →

    IHC-P: Use a concentration of 10 - 50 µg/ml.Antigen retrieval is not essential but may optimise staining.

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    IHC-Fr

     IHC-Fr: Use a concentrat...Read more →

    IHC-Fr: Use a concentration of 10 - 50 µg/ml.

Target

Function

Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.

Tissue specificity

Platelets.

Sequence similarities

Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.

Cellular localization

Membrane.

Target information above from: UniProt accessionQ9BV40 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • EDB antibody
  • Endobrevin antibody
  • VAMP 5 antibody
  • VAMP 8 antibody
  • VAMP-8 antibody
  • VAMP5 antibody
  • VAMP8 antibody
  • VAMP8_HUMAN antibody
  • Vesicle associated membrane protein 8 antibody
  • Vesicle-associated membrane protein 8 antibody
see all

References for Anti-VAMP8 antibody (ab81025)

This product has been referenced in:

  • Stoeckelhuber Met al. Human axillary apocrine glands: proteins involved in the apocrine secretory mechanism. Histol Histopathol 26:177-84 (2011). IHC-P; Human.Read more (PubMed: 21154231) »

See 1 publication for this product

Publishing research using ab81025? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"