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Products:Neuroscience >> Neurotransmission >> Secretory Vesicles >> SNAPs & SNAREs
Overview
Product name
VAMP8 protein (His tag)
Protein description
Recombinant fragment, corresponding to amino acids 1-76 of human VAMP8 with His tag; 96 amino acids, 10.9kDa. Swiss ID = Q9BV40.
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Purification notes
ab79141 is purified using conventional chromatography techniques.
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 30% Glycerol, 20mM Tris, pH 8.0
Concentration
Concentration information loading...
Sequence notes
MGSSHHHHHH SSGLVPRGSH MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKM
Research areas
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Neuroscience >> Neurotransmission >> Secretory Vesicles >> SNAPs & SNAREs
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SDS-PAGE - VAMP8 protein (His tag) (ab79141)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab79141 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
Protein info
Function
Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.
Tissue specificity
Platelets.
Sequence similarities
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ9BV40
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
VAMP8 protein (His tag) images:
SDS-PAGE - VAMP8 protein (His tag) (ab79141)
15% SDS-PAGE showing ab79141 at approximately 11kDa (3µg).
References for VAMP8 protein (His tag) (ab79141)
ab79141 has not yet been referenced specifically in any publications.
Publishing research using ab79141? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"