Anti-VCAM1 antibody [MR106] (Biotin) (ab95542)

Overview

  • Product nameAnti-VCAM1 antibody [MR106] (Biotin)
    See all VCAM1 primary antibodies
  • Description
    Mouse monoclonal [MR106] to VCAM1 (Biotin)
  • ConjugationBiotin
  • Tested applicationsFlow Cytmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Rat VCAM1 transfected L5178Y cells.

  • Positive control
    • Rat bone marrow cells

Properties

Applications

Our Abpromise guarantee covers the use of ab95542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.125-0.25µg for 105-8 cells. A final volume of 100 µL is recommended for staining the cell sample.

Target

  • FunctionImportant in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • Tissue specificityExpressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • Sequence similaritiesContains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • DomainEither the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • Post-translational
    modifications
    Sialoglycoprotein.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

Anti-VCAM1 antibody [MR106] (Biotin) images

  • Staining of Rat bone marrow cells with 0.125 µg of Mouse IgG1 ? Isotype Control Biotin (left) or 0.125 µg of ab95542 (right), followed by Streptavidin PE.
    Total viable cells were used for analysis.

References for Anti-VCAM1 antibody [MR106] (Biotin) (ab95542)

ab95542 has not yet been referenced specifically in any publications.

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