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Product Name
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VDAC/Porin antibody - Mitochondrial Marker
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See all VDAC/Porin antibodies (7)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to VDAC/Porin - Mitochondrial Marker
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Immunogen
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Recombinant fragment (Human) (N terminal). Porin 31HL from EBV-transformed human B-lymphocytes was used as the immunogen. Corresponds to mAb 4 in the literature.
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Reacts with
(species key)
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Hu, Ms
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Tested applications
(see key)
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ICC, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Mitochondrial outer membrane and plasma membrane.
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Research areas
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Signal Transduction >> Metabolism >> Plasma Membrane >> Channels
Signal Transduction >> Metabolism >> Mitochondrial
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Mitochondria
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Relevance
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Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2b
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Purity
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>90% by SDS-PAGE
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50 mM NaOAc, 500mM Sodium chloride, 50mM Tris HCl. pH 7.0 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this VDAC/Porin antibody - Mitochondrial Marker is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to VDAC/Porin
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