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Western blot - VDAC1/Porin - HRP antibody (HRP) (ab40747)
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Product Name
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VDAC1/Porin - HRP antibody (HRP)
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to VDAC1/Porin - HRP (HRP)
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human VDAC1/Porin - HRP . (Peptide available as ab16131.)
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Reacts with
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Hu, Ms, Rat
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Predicted to react
(species key)
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Chk, Cow, Pig, Rb, Shp, Zfsh, Orngt
(Due to sequence homology)
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/5000. Detects a band of approximately 34 kDa (predicted molecular weight: 31 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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This antibody gave a positive signal in the following lysates:
Caco-2 Whole Cell
HepG2 Whole Cell
Rat Kidney Tissue
HeLa Whole Cell
SW480 Whole Cell
Mouse Skeletal Muscle Tissue
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Cellular localization
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Outer membranes of all eukaryotic mitochondria
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Research areas
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Isotype/Loading Controls >> Loading Controls >> VDAC1 - Mitochondrial Preps
Signal Transduction >> Metabolism >> Mitochondrial
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Mitochondria
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Relevance
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The Voltage-Dependent Anion Channel (VDAC or mitochondrial Porin) is an outer membrane mitochondrial protein. The VDAC protein is thought to form the major pores through which adenine nucleotides cross the outer mitochondrial membrane. VDAC has also been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT) and cyclophilin D (CypD) is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Conjugation
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Horse Radish Peroxidase
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this VDAC1/Porin - HRP antibody (HRP) is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for VDAC1/Porin - HRP antibody (HRP) images, references, products related to ab40747 and other tools.
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VDAC1/Porin - HRP antibody (HRP) images:
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Search PubMed (MEDLINE) for references to VDAC1/Porin - HRP
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VDAC1/Porin - HRP antibody (HRP) - more information
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Customer reviews (feedback) regarding VDAC1/Porin - HRP antibody (HRP) |
Customer FAQs regarding VDAC1/Porin - HRP antibody (HRP) |
Protocols for VDAC1/Porin - HRP antibody (HRP) |
Price and availability of products related to VDAC1/Porin - HRP antibody (HRP) |
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VDAC1/Porin - HRP antibody (HRP) - related products:
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VDAC1/Porin - HRP antibody (HRP) - other tools:
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Contact Abcam with a Technical Enquiry about VDAC1/Porin - HRP antibody (HRP) |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Western blot - VDAC1/Porin - HRP antibody (HRP) (ab40747)