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Anti-VDAC3 antibody (ab80452)

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Overview

Product name

Anti-VDAC3 antibody
See all VDAC3 products (2) ...

Description

Rabbit polyclonal to VDAC3

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Rabbit, Cow, Dog, Pig, Zebrafish, Orangutan

Immunogen

Synthetic peptide: TQKWNTDNTL GTEISWENKL AEGLKLTLDT IFVPNTGKKS GKLKASYKRD , corresponding to N terminal amino acids 73-122 of Human VDAC3 (NP_005653)

TQKWNTDNTL GTEISWENKL AEGLKLTLDT IFVPNTGKKS GKLKASYKRD

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Fetal heart lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

ab80452 is purified by a peptide affinity chromatography method.

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Metabolism >> Energy Metabolism
Cell Biology >> Apoptosis >> Mitochondrial

  • Western blot - VDAC3 antibody (ab80452)Western blot - VDAC3 antibody (ab80452) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab80452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 µg/mlDetects a band of approximately 31 kDa (predicted molecular weight: 31 kDa).

Target

Relevance

The Voltage-Dependant Anion Channel (VDAC3) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane.

Cellular localization

Mitochondrial outer membrane.

Alternative names

  • hVDAC3 antibody
  • mVDAC3 antibody
  • Outer mitochondrial membrane protein porin 3 antibody
  • voltage dependent anion channel 3 antibody

Database links

see all

Anti-VDAC3 antibody images:

  Western blot - VDAC3 antibody (ab80452)

Western blot - VDAC3 antibody (ab80452)

Anti-VDAC3 antibody (ab80452) at 1 µg/ml + Fetal heart lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 31 kDa
Observed band size : 31 kDa

References for Anti-VDAC3 antibody (ab80452)

ab80452 has not yet been referenced specifically in any publications.

Publishing research using ab80452? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"