Anti-VEGFB antibody (ab185696)
Key features and details
- Rabbit polyclonal to VEGFB
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-VEGFB antibody
See all VEGFB primary antibodies -
Description
Rabbit polyclonal to VEGFB -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Cow, Human -
Immunogen
Recombinant fragment corresponding to Human VEGFB aa 1 to the C-terminus.
Database link: P49765 -
Positive control
- WB: Mouse heart tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab185696 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 22 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 22 kDa. |
Target
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Function
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. -
Tissue specificity
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. -
Sequence similarities
Belongs to the PDGF/VEGF growth factor family. -
Post-translational
modificationsVEGF-B186 is O-glycosylated. -
Cellular localization
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. - Information by UniProt
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Database links
- Entrez Gene: 7423 Human
- Entrez Gene: 22340 Mouse
- Omim: 601398 Human
- SwissProt: P49765 Human
- SwissProt: P49766 Mouse
- Unigene: 78781 Human
- Unigene: 15607 Mouse
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Form
There are 2 isoforms produced by alternative splicing. -
Alternative names
- Vascular endothelial growth factor B antibody
- Vascular endothelial growth factor-related factor antibody
- VEGF B antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (7)
ab185696 has been referenced in 7 publications.
- Yen JH et al. Improved Wound Healing by Naringin Associated with MMP and the VEGF Pathway. Molecules 27:N/A (2022). PubMed: 35268795
- Zhang Y et al. Effect of intravitreal conbercept injection on VEGF-A and -B levels in the aqueous and vitreous humor of patients with proliferative diabetic retinopathy. Exp Ther Med 21:332 (2021). PubMed: 33732305
- Zhu X et al. Class A1 scavenger receptor prevents obesity-associated blood pressure elevation through suppressing overproduction of vascular endothelial growth factor B in macrophages. Cardiovasc Res 117:547-560 (2021). PubMed: 32044963
- Wang H et al. Pigment Epithelial-Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia. J Am Heart Assoc 8:e013028 (2019). PubMed: 31711388
- Rothhammer V et al. Microglial control of astrocytes in response to microbial metabolites. Nature 557:724-728 (2018). PubMed: 29769726
- Lv YX et al. VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve Stimulation. Cell Physiol Biochem 48:433-449 (2018). PubMed: 30016789
- Lu B et al. Effect of CCL2 siRNA on proliferation and apoptosis in the U251 human glioma cell line. Mol Med Rep 16:3387-3394 (2017). PubMed: 28714025