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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Purification notes The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
Use a concentration of 0.5 µg/ml. For sandwich ELISA, use this antibody as Detection at 0.5µg/ml with
Ab76863 as Capture.
Function Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Tissue specificity Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
Sequence similarities Belongs to the PDGF/VEGF growth factor family.
Post-translational modifications VEGF-B186 is O-glycosylated.
Cellular localization Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Information by UniProt
Form There are 2 isoforms produced by alternative splicing.
Vascular endothelial growth factor B antibody
VEGF B antibody
VEGF related factor antibody
Anti-VEGFB antibody images
References for Anti-VEGFB antibody (ab58461)
This product has been referenced in:
et al. Vascular protection by Angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke. PLoS One 6:e24551 (2011).
Read more (PubMed: 21912702) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"