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Overview

  • Product nameAnti-VEGFB antibodySee all VEGFB primary antibodies ...
  • Description
    Mouse polyclonal to VEGFB
  • Tested applicationsSandwich ELISA, WB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length human VEGFB protein (NP_003368) with a 26 kDa tag.

  • Positive controlVEGFB transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab76863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Sandwich ELISA sELISA: Use a concentration of 5 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to VEGFB (ab58461). For sandwich ELISA, use this antibody as Capture at 5µg/ml with ab58461 as Detection.
WB WB: Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 22 kDa.

Target

  • FunctionGrowth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
  • Tissue specificityExpressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
  • Sequence similaritiesBelongs to the PDGF/VEGF growth factor family.
  • Post-translational
    modifications
    VEGF-B186 is O-glycosylated.
  • Cellular localizationSecreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
  • Target information above from: UniProt accession P49765 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • FormThere are 2 isoforms produced by alternative splicing.
    • Alternative names
        Vascular endothelial growth factor B antibodyVascular endothelial growth factor B precursor antibodyVEGF B antibody
        VEGF related factor antibodyVEGF-B antibodyVEGF-related factor antibodyVegfb antibodyVEGFB_HUMAN antibodyVEGFL antibodyVRF antibody
      see all

    Anti-VEGFB antibody images

    Protocols

    References for Anti-VEGFB antibody (ab76863)

    ab76863 has not yet been referenced specifically in any publications.

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