Anti-VIP antibody (ab22736)
Key features and details
- Rabbit polyclonal to VIP
- Suitable for: IHC-Fr, IHC-P
- Reacts with: Rat, Sheep, Dog, Human, Pig
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-VIP antibody
See all VIP primary antibodies -
Description
Rabbit polyclonal to VIP -
Host species
Rabbit -
Specificity
ab22736 reacts with Vasoactive Intestinal (poly)Peptide (VIP). -
Tested applications
Suitable for: IHC-Fr, IHC-Pmore details -
Species reactivity
Reacts with: Rat, Sheep, Dog, Human, Pig -
Immunogen
Full length native protein (purified) (Pig) conjugated to KLH by a Glutaraldehyde linker.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab22736 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-Fr | (3) | |
IHC-P |
Notes |
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IHC-P: 1/400 - 1/1600.
Notes: Dilute to working strength with PBS containing 0.1% w/v sodium azide.
Store diluted antibodies at 2-4°C(do not freeze) and use within 1 month.
using overnight incubation and indirect immunofluorescence procedure.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
PHM and PHV also cause vasodilation. -
Sequence similarities
Belongs to the glucagon family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 7432 Human
- Entrez Gene: 100500718 Pig
- Entrez Gene: 117064 Rat
- Entrez Gene: 100145884 Sheep
- Omim: 192320 Human
- SwissProt: P01282 Human
- SwissProt: P01284 Pig
- SwissProt: P01283 Rat
see all -
Alternative names
- Peptide histidine methioninamide 27 antibody
- Peptide histidine valine 42 antibody
- PHM27 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (18)
ab22736 has been referenced in 18 publications.
- Nestor-Kalinoski A et al. Unique Neural Circuit Connectivity of Mouse Proximal, Middle, and Distal Colon Defines Regional Colonic Motor Patterns. Cell Mol Gastroenterol Hepatol 13:309-337.e3 (2022). PubMed: 34509687
- Kras K et al. Morphology and Chemical Coding of Rat Duodenal Enteric Neurons following Prenatal Exposure to Fumonisins. Animals (Basel) 12:N/A (2022). PubMed: 35565482
- Barr JL et al. Intra-Tumoral Nerve-Tracing in a Novel Syngeneic Model of High-Grade Serous Ovarian Carcinoma. Cells 10:N/A (2021). PubMed: 34944001
- Puzio I et al. Alterations in Small Intestine and Liver Morphology, Immunolocalization of Leptin, Ghrelin and Nesfatin-1 as Well as Immunoexpression of Tight Junction Proteins in Intestinal Mucosa after Gastrectomy in Rat Model. J Clin Med 10:N/A (2021). PubMed: 33450994
- Casalia ML et al. Interneuron Origins in the Embryonic Porcine Medial Ganglionic Eminence. J Neurosci 41:3105-3119 (2021). PubMed: 33637558