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Anti-VIP antibody (ab8556)

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Overview

Product name

Anti-VIP antibody
See all VIP products (7) ...

Description

Rabbit polyclonal to VIP

Specificity

This antibody reacts with a 3 kD vasointestinal peptide (VIP) localized in nerve fibers in the central and peripheral nervous system. The VIP producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.

Tested applications

WB, IP, IHC-FoFr, IHC-P, IHC-Frmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

VIP of human origin.

Positive control

Brain

Properties

Form

Liquid

Storage instructions

Store at +4°C. Do not freeze.

Storage buffer

pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS

Concentration

Concentration information loading...

Purity

Protein G purified

Purification notes

After solid-phase absorption this antibody is filtered through a 0.22 µm filter, vialed and lyophilized.

Primary antibody notes

This antibody detects ganglion cells in both the superficial and deep plexus of the wall of the small bowel in human.

Clonality

Polyclonal

Isotype

IgG

Light chain type

unknown

Research areas

Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones

Applications

Show applications key

Our Abpromise guarantee covers the use of ab8556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: Use at an assay depe...Read more →

    WB: Use at an assay dependent concentration.

  • ShowHide

    IP

     IP: Use at an assay depe...Read more →

    IP: Use at an assay dependent concentration.

  • ShowHide

    IHC-FoFr

     IHC-FoFr: Use at an assa...Read more →

    IHC-FoFr: Use at an assay dependent dilution.

  • IHC-P

     IHC-P: 1/20

    IHC-P: 1/20

  • ShowHide

    IHC-Fr

     IHC-Fr: Use at an assay ...Read more →

    IHC-Fr: Use at an assay dependent dilution.

Target

Function

VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
PHM and PHV also cause vasodilation.

Sequence similarities

Belongs to the glucagon family.

Cellular localization

Secreted.

Target information above from: UniProt accessionP01282 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • MGC13587 antibody
  • Peptide histidine methioninamide 27 antibody
  • Peptide histidine valine 42 antibody
  • PHM 27 antibody
  • PHM27 antibody
  • PHV42 antibody
  • Vasoactive intestinal peptide antibody
  • Vasoactive intestinal polypeptide antibody
  • VIP antibody
  • VIP peptides antibody
  • VIP peptides precursor antibody
  • VIP_HUMAN antibody
see all

Database links

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References for Anti-VIP antibody (ab8556)

This product has been referenced in:

  • Samarasinghe AEet al. Spatio-temporal localization of vasoactive intestinal peptide and neutral endopeptidase in allergic murine lungs. Regul Pept 164:151-7 (2010). IHC; Mouse.Read more (PubMed: 20566347) »

See 1 publication for this product

Publishing research using ab8556? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"