Anti-VNN1/Vanin-1 antibody (ab96171)
Key features and details
- Rabbit polyclonal to VNN1/Vanin-1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-VNN1/Vanin-1 antibody
See all VNN1/Vanin-1 primary antibodies -
Description
Rabbit polyclonal to VNN1/Vanin-1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human VNN1/Vanin-1 aa 232-427 (internal sequence).
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Positive control
- H1299, HeLa or HepG2 cell lines.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96171 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 57 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 57 kDa. |
Target
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Function
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. -
Tissue specificity
Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin. -
Sequence similarities
Belongs to the CN hydrolase family. BTD/VNN subfamily.
Contains 1 CN hydrolase domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8876 Human
- Omim: 603570 Human
- SwissProt: O95497 Human
- Unigene: 12114 Human
- Unigene: 720659 Human
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Alternative names
- HDLCQ8 antibody
- High density lipoprotein cholesterol level quantitative trait locus 8, included antibody
- Pantetheinase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab96171 has been referenced in 1 publication.
- Povero D et al. Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells. Sci Signal 6:ra88 (2013). Neutralising ; Human . PubMed: 24106341