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Overview

  • Product nameVTA1 protein (Human)
  • Protein descriptionRecombinant full length Human VTA1 expressed in Saccharomyces cerevisiae, 307 amino acids (34 kDa), UniProt Q9NP79. Protein is tagged with 26 kDa proprietary tag.
  • Expression hostSaccharomyces cerevisiae

    • Properties

  • Purity> 90 % by SDS-PAGE
  • Purification notesab88925 is purifed by affinity chromatography.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5
  • Concentration information loading...
  • Sequence notesMAALAPLPPLPAQFKSIQHHLRTAQEHDKRDPVVAYYCRL YAMQTGMKIDSKTPECR KFLSKLMDQLEALKKQLGDNE AITQEIVGCAHLENYALKMFLYADNEDRAGRFHKNM IK SFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCL KNGETPQAGPVGIEE DNDIEENEDAGAASLPTQPTQPS SSSTYDPSNMPSGNYTGIQIPPGAHAPANTPAEV PHST GVASNTIQPTPQTIPAIDPALFNTISQGDVRLTPEDFARA QKYCKYAGSALQY EDVSTAVQNLQKALK LLTTGRE
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab88925 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        C6orf55Chromosome 6 open reading frame 55Dopamine responsive protein DRG 1
        Dopamine-responsive gene 1 proteinDRG 1DRG-1DRG1Homolog of mouse SKD1 binding protein 1LIP5LYST interacting protein 5LYST-interacting protein 5My012SBP1SKD1 binding protein 1SKD1-binding protein 1Vacuolar protein sorting-associated protein VTA1 homologVps20 associated 1 homolog (S. cerevisiae)VTA1VTA1_HUMAN
      see all
  • FunctionInvolved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.
  • Sequence similaritiesBelongs to the VTA1 family.
  • Cellular localizationCytoplasm. Endosome membrane.

    • Target information above from: UniProt accession Q9NP79 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for VTA1 protein (Human) (ab88925)

    ab88925 has not yet been referenced specifically in any publications.

    Publishing research using ab88925 ? Please let us know so that we can cite the reference in this datasheet

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