Biotin Anti-Vasopressin antibody (ab48322)
Key features and details
- Biotin Rabbit polyclonal to Vasopressin
- Suitable for: ELISA, RIA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
Overview
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Product name
Biotin Anti-Vasopressin antibody
See all Vasopressin primary antibodies -
Description
Biotin Rabbit polyclonal to Vasopressin -
Host species
Rabbit -
Conjugation
Biotin -
Tested applications
Suitable for: ELISA, RIAmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Xenopus laevis, Pufferfish, Zebrafish -
Immunogen
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49.73% PBS, 50% Glycerol (glycerin, glycerine), 0.25% BSA -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab48322 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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RIA |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
RIA
Use at an assay dependent concentration. |
Target
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Relevance
Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 396101 Chicken
- Entrez Gene: 280728 Cow
- Entrez Gene: 403579 Dog
- Entrez Gene: 551 Human
- Entrez Gene: 11998 Mouse
- Entrez Gene: 396995 Pig
- Entrez Gene: 24221 Rat
- Omim: 192340 Human
see all -
Alternative names
- ADH antibody
- Antidiuretic hormone antibody
- Arginine vasopressin neurophysin II antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab48322 has been referenced in 1 publication.
- Zhou ZB et al. Sevoflurane-induced down-regulation of hippocampal oxytocin and arginine vasopressin impairs juvenile social behavioral abilities. J Mol Neurosci 56:70-7 (2015). WB . PubMed: 25417719