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Products:Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Adapters
Overview
Product name
Vesicle docking protein p115 peptide (950-961)
See all Vesicle docking protein p115 products (3) ...
Protein description
Synthetic peptide: C-DESEDPGKDLDH, corresponding to C terminal amino acids 950-961 of Human Vesicle docking protein p115. This peptide was used as an immunogen for ab40822 - Vesicle docking protein p115 antibody.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration
Concentration information loading...
Sequence
C-DESEDPGK DLDH
Research areas
Signal Transduction >> Protein Trafficking >> Golgi Proteins
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Adapters
Protein info
Function
General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.
Sequence similarities
Belongs to the VDP/USO1/EDE1 family.
Contains 10 ARM repeats.
Domain
Composed of a globular head, an elongated tail (coiled-coil) and a highly acidic C-terminal domain.
Post-translational
modifications
Phosphorylated in a cell cycle-specific manner; phosphorylated in interphase but not in mitotic cells. Dephosphorylated protein associates with the Golgi membrane; phosphorylation promotes dissociation.
Cellular localization
Cytoplasm > cytosol. Golgi apparatus membrane. Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes.
Target information above from: UniProt accessionO60763
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for Vesicle docking protein p115 peptide (950-961) (ab45833)
ab45833 has not yet been referenced specifically in any publications.
Publishing research using ab45833? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"