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Product Name
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WAVE 1 antibody [1.T.4]
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See all WAVE 1 antibodies (7)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [1.T.4] to WAVE 1
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Immunogen
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His6 fusion protein corresponding to full-length rat WAVE1.
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Reacts with
(species key)
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Rat
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Specificity
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Recognizes rat WAVE1 at MW 84kDa.
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/1000 - 1/5000. Predicted molecular weight: 84 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Rat brain cytosol.
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Cellular localization
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Cytoplasmic; Concentrated in Rac regulated membrane ruffling areas.
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Research areas
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Cancer >> Tumor biomarkers >> Other
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> Other
Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Assembly
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Relevance
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The Wiskott Aldrich syndrome family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. They play an important part in cell motility. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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1.T.4
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Isotype
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IgG
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Purity
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Ascites
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Storage buffer
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Preservative: 0.05% Sodium Azide
Constituents: 30% Glycerol Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this WAVE 1 antibody [1.T.4] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to WAVE 1
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WAVE 1 antibody [1.T.4] - more information
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Customer reviews (feedback) regarding WAVE 1 antibody [1.T.4] |
Customer FAQs regarding WAVE 1 antibody [1.T.4] |
Protocols for WAVE 1 antibody [1.T.4] |
Price and availability of products related to WAVE 1 antibody [1.T.4] |
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WAVE 1 antibody [1.T.4] - other tools:
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