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Products:Signal Transduction >> Metabolism >> Amino Acids
Overview
Product name
Anti-WBSCR22 antibody
See all WBSCR22 products (3) ...
Description
Mouse polyclonal to WBSCR22
Specificity
This antibody is reactive against mammalian transfected lysate.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length protein, corresponding to amino acids 1-281 of Human WBSCR22
Positive control
Transfected 293T cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> DNA methylation >> Methylated DNA Associated
Signal Transduction >> Metabolism >> Amino Acids
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Western blot - WBSCR22 antibody (ab70440)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab70440 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: 1/500 - 1/1000. Detects a band of approximately 32 kDa (predicted molecular weight: 32 kDa).
Detection Antibody.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Methyltransferase that may act on DNA.
Tissue specificity
Strongly expressed in heart, skeletal muscle and kidney. Also expressed in spleen, liver, lung and testis.
Involvement in disease
Note=WBSCR22 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR22 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
Sequence similarities
Belongs to the methyltransferase superfamily.
Cellular localization
Nucleus.
Target information above from: UniProt accessionO43709
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- HASJ4442 antibody
- HUSSY 3 antibody
- HUSSY3 antibody
see all
Database links
- Entrez Gene: 114049 Human
- SwissProt: O43709 Human
- Unigene: 647063 Human
Anti-WBSCR22 antibody images:
Western blot - WBSCR22 antibody (ab70440)
All lanes : Anti-WBSCR22 antibody (ab70440) at 1/500 dilution
Lane 1 : WBSCR22 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 32 kDa
Observed band size : 32 kDa
References for Anti-WBSCR22 antibody (ab70440)
ab70440 has not yet been referenced specifically in any publications.
Publishing research using ab70440? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"