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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> Translation >> tRNAs
Overview
Product name
Anti-WDR4 antibody
See all WDR4 products (6) ...
Description
Chicken polyclonal to WDR4
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length protein, corresponding to amino acids 1-266 of Human WDR4
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgY
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> Translation >> tRNAs
Applications
Show applications key
Our Abpromise guarantee covers the use of ab37494 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 45 kDa.
Target
Function
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational change of the catalytic subunit.
Pathway
tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
Sequence similarities
Belongs to the WD repeat TRM82 family.
Contains 4 WD repeats.
Cellular localization
Nucleus.
Target information above from: UniProt accessionP57081
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- OTTHUMP00000109401 antibody
- OTTHUMP00000109402 antibody
- TRM82 antibody
see all
Database links
- Entrez Gene: 10785 Human
- Omim: 605924 Human
- SwissProt: P57081 Human
- SwissProt: Q9BVM5 Human
- Unigene: 248815 Human
References for Anti-WDR4 antibody (ab37494)
ab37494 has not yet been referenced specifically in any publications.
Publishing research using ab37494? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"