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IHC-P - WDR4 antibody (ab56765)
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Western blot - WDR4 antibody (ab56765)
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Product Name
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WDR4 antibody
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See all WDR4 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to WDR4
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Immunogen
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Recombinant full length protein, corresponding to amino acids 1-267 of Human WDR4
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 1 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> Translation >> tRNAs
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Relevance
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WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR4 is required for 7-methylguanosine modification of tRNA. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants, two of which diverge at the 3' UTR and thus encode the same protein products.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this WDR4 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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WDR4 antibody images:
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 IHC-P - WDR4 antibody (ab56765)
WDR4 antibody (ab56765) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human small Intestine.
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Western blot - WDR4 antibody (ab56765)
Predicted band size : 45 kDa
WDR4 antibody (ab56765) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to WDR4
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WDR4 antibody - more information
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Customer reviews (feedback) regarding WDR4 antibody |
Customer FAQs regarding WDR4 antibody |
Protocols for WDR4 antibody |
Price and availability of products related to WDR4 antibody |
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WDR4 antibody - other tools:
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Contact Abcam with a Technical Enquiry about WDR4 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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