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WDR5 peptide (ab24388)

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Overview

Product name

WDR5 peptide
See all WDR5 products (3) ...

Protein description

Synthetic peptide derived from within residues 300 to the C-terminus of Human WDR5. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab22512 - .

Protein length

334 amino acids

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Remodeling >> Trithorax
Epigenetics and Nuclear Signaling >> Chromatin Binding Proteins >> Methyl Lysine
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation

Applications

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Our Abpromise guarantee covers the use of ab24388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Blocking

     

Application notes

BL: Use at a concentration of 1 µg/ml.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Protein info

Function

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May regulate osteoblasts differentiation.

Sequence similarities

Belongs to the WD repeat WDR5/wds family.
Contains 7 WD repeats.

Cellular localization

Nucleus.

Target information above from: UniProt accessionP61964 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for WDR5 peptide (ab24388)

ab24388 has not yet been referenced specifically in any publications.

Publishing research using ab24388? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"