Overview
- Product nameAnti-Wnt1 antibodySee all Wnt1 primary antibodies ...
- DescriptionRabbit polyclonal to Wnt1
- Specificityab62703 detects endogenous levels of total Wnt1 protein.
- Tested applicationsELISA, IHC-P more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse - Immunogen
Synthetic peptide derived from an internal region of human Wnt1.
- Positive controlHuman breast carcinoma tissue.
Properties
- FormLiquid
- Storage instructionsStore at -20°C. Stable for 12 months at -20°C
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4 -
Concentration information loading... - PurityImmunogen affinity purified
- Purification notesab62703 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab62703 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| ELISA | ELISA: 1/10000. |
| IHC-P | IHC-P: 1/50 - 1/100. |
Target
- FunctionLigand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.
- Sequence similaritiesBelongs to the Wnt family.
- Cellular localizationSecreted > extracellular space > extracellular matrix.
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Database links
- Entrez Gene: 7471 Human
- Entrez Gene: 22408 Mouse
- Omim: 164820 Human
- SwissProt: P04628 Human
- SwissProt: P04426 Mouse
- Unigene: 248164 Human
- Unigene: 1123 Mouse
Target information above from: UniProt accession
P04628
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- INT 1 antibodyINT1 antibodyMurine mammary tumor virus integration site 1 antibody
- Oncogene INT1 antibodyProto oncogene protein Wnt 1 antibodyProto-oncogene Int-1 homolog antibodyProto-oncogene Wnt-1 antibodyWingless type MMTV integration site family member 1 antibodyWnt 1 antibodywnt1 antibodyWnt1 proto oncogene protein precursor antibodyWNT1_HUMAN antibody
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Anti-Wnt1 antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Wnt1 antibody (ab62703)ab62703 at 1/50 - 1/100 dilution staining Wnt1 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
References for Anti-Wnt1 antibody (ab62703)
ab62703 has not yet been referenced specifically in any publications.
