Overview

  • Product nameAnti-XAB1 antibodySee all XAB1 primary antibodies ...
  • Description
    Rabbit polyclonal to XAB1
  • Tested applicationsWB, IP more details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide: DTDDIDHRVTEESHEEP, corresponding to amino acids 339-355 of Human XAB1 conjugated to KLH via a N terminal added cysteine residue.

  • Positive control
    • HEK-293T cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab50265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
IP
  • Application notesIP: Use at a concentration of 5 - 10 µg/ml lysate
    WB: Use at a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 42 kDa.
    Staining of the MBDin/XAB1 band in Western blotting is specifically inhibited by the
    immunizing peptide.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionForms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA.
    • Tissue specificityExpressed ubiquitously.
    • Sequence similaritiesBelongs to the GPN-loop GTPase family.
    • Cellular localizationCytoplasm.
    • Target information above from: UniProt accession Q9HCN4 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • ATP(GTP) binding protein antibody
      • ATPBD1A antibody
      • FLJ51176 antibody
      • GPN loop GTPase 1 antibody
      • GPN-loop GTPase 1 antibody
      • Gpn1 antibody
      • GPN1_HUMAN antibody
      • MBD2 interacting protein antibody
      • MBD2-interacting protein antibody
      • MBDIN antibody
      • NTPBP antibody
      • RNA polymerase II associated protein 4 antibody
      • RPAP4 antibody
      • XAB1 antibody
      • XPA binding protein 1 antibody
      • XPA binding protein 1 GTPase antibody
      • XPA binding protein 1, GTPase antibody
      • XPA-binding protein 1 antibody
      see all

    References for Anti-XAB1 antibody (ab50265)

    This product has been referenced in:
    • Dong L  et al. Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism. Cancer Res 70:3547-56 (2010). WB ; Human . Read more (PubMed: 20388774) »

    See 1 Publication for this product

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