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Anti-XAB1 antibody (ab50265)

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Overview

Product name

Anti-XAB1 antibody
See all XAB1 products (3) ...

Description

Rabbit polyclonal to XAB1

Tested applications

WB, IPmore details

Cross reactivity

Reacts with

Mouse, Human

Immunogen

Synthetic peptide: DTDDIDHRVTEESHEEP, corresponding to amino acids 339-355 of Human XAB1 conjugated to KLH via a N terminal added cysteine residue.

DTDDIDHRVT EESHEEP

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

HEK-293T cell lysates

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: 1% BSA, 0.01M PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Nucl. Excision Repair
Epigenetics and Nuclear Signaling >> DNA methylation >> Methylated DNA

Applications

Show applications key

Our Abpromise guarantee covers the use of ab50265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB

     

  • IP

     

Application notes

IP: Use at a concentration of 5 - 10 µg/ml lysate
WB: Use at a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 42 kDa.
Staining of the MBDin/XAB1 band in Western blotting is specifically inhibited by the
immunizing peptide.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA.

Tissue specificity

Expressed ubiquitously.

Sequence similarities

Belongs to the GPN-loop GTPase family.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionQ9HCN4 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • ATP(GTP) binding protein antibody
  • ATPBD1A antibody
  • FLJ51176 antibody
  • GPN loop GTPase 1 antibody
  • GPN-loop GTPase 1 antibody
  • Gpn1 antibody
  • GPN1_HUMAN antibody
  • MBD2 interacting protein antibody
  • MBD2-interacting protein antibody
  • MBDIN antibody
  • NTPBP antibody
  • XPA binding protein 1 antibody
  • XPA binding protein 1 GTPase antibody
  • XPA binding protein 1, GTPase antibody
  • XPA-binding protein 1 antibody
see all

Database links

References for Anti-XAB1 antibody (ab50265)

This product has been referenced in:

  • Dong Let al. Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism. Cancer Res 70:3547-56 (2010). WB; Human.Read more (PubMed: 20388774) »

See 1 publication for this product

Publishing research using ab50265? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"