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Products:Epigenetics and Nuclear Signaling >> DNA methylation >> Methylated DNA
Overview
Product name
Anti-XAB1 antibody
See all XAB1 products (3) ...
Description
Mouse monoclonal to XAB1
Tested applications
WB, IHC-P, ICC/IFmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment, corresponding to amino acids 9-119 of Human XAB1
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Applications
Show applications key
Our Abpromise guarantee covers the use of ab56974 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Predicted molecular weight: 42 kDa.
IHC-P: Use a concentration of 3 µg/ml
ICC/IF: Use at an assay dependent concentration. (PubMed: 21768307)
Target
Function
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA.
Tissue specificity
Expressed ubiquitously.
Sequence similarities
Belongs to the GPN-loop GTPase family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionQ9HCN4
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ATP(GTP) binding protein antibody
- ATPBD1A antibody
- FLJ51176 antibody
see all
Database links
- Entrez Gene: 11321 Human
- Omim: 611479 Human
- SwissProt: Q9HCN4 Human
- Unigene: 18259 Human
Anti-XAB1 antibody images:
IHC-P - XAB1 antibody (ab56974)
XAB1 antibody (ab56974) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human stomach.
Western blot - XAB1 antibody (ab56974)
XAB1 antibody (ab56974) at 1ug/lane + HL-60 cell lysate at 25ug/lane.
References for Anti-XAB1 antibody (ab56974)
This product has been referenced in:
- Carré C & Shiekhattar R Human GTPases associate with RNA polymerase II to mediate its nuclear import. Mol Cell Biol 31:3953-62 (2011). WB, ICC/IF; Human.Read more (PubMed: 21768307) »
See 1 publication for this product
Publishing research using ab56974? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"