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IHC-P - XAB2 antibody (ab57515)
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Western blot - XAB2 antibody (ab57515)
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Product Name
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XAB2 antibody
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See all XAB2 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to XAB2
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Immunogen
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Recombinant full length protein, corresponding to amino acids 1-856 of Human XAB2
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear. Note: Detected in the splicing complex carrying pre-mRNA
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Nucl. Excision Repair
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Relevance
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XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription coupled repair and transcription.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2b
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this XAB2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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XAB2 antibody images:
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 IHC-P - XAB2 antibody (ab57515)
XAB2 antibody (ab57515) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
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Western blot - XAB2 antibody (ab57515)
Predicted band size : 100 kDa
XAB2 antibody (ab57515) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to XAB2
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XAB2 antibody - more information
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Customer reviews (feedback) regarding XAB2 antibody |
Customer FAQs regarding XAB2 antibody |
Protocols for XAB2 antibody |
Price and availability of products related to XAB2 antibody |
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XAB2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about XAB2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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