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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Nucl. Excision Repair
Overview
Product name
Anti-XAB2 antibody
See all XAB2 products (6) ...
Description
Mouse monoclonal to XAB2
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-856 of Human XAB2
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2b
Light chain type
kappa
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Nucl. Excision Repair
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57515 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription coupled repair and transcription.
Cellular localization
Nuclear. Note: Detected in the splicing complex carrying pre-mRNA
Alternative names
- crn-related protein kim1 antibody
- DKFZp762C1015 antibody
- HCNP antibody
see all
Database links
- Entrez Gene: 56949 Human
- Omim: 610850 Human
- SwissProt: Q9HCS7 Human
- Unigene: 9822 Human
Anti-XAB2 antibody images:
IHC-P - XAB2 antibody (ab57515)
XAB2 antibody (ab57515) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
Western blot - XAB2 antibody (ab57515)
XAB2 antibody (ab57515) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-XAB2 antibody (ab57515)
ab57515 has not yet been referenced specifically in any publications.
Publishing research using ab57515? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"