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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Nucl. Excision Repair
Overview
Product name
Anti-XAB2 antibody
See all XAB2 products (6) ...
Description
Rabbit polyclonal to XAB2
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide, corresponding to amino acids 840-855 of Human XAB2.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Nucl. Excision Repair
Applications
Show applications key
Our Abpromise guarantee covers the use of ab7289 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Detects a band of approximately 100 kDa (predicted molecular weight: 100 kDa).
Target
Relevance
XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription coupled repair and transcription.
Cellular localization
Nuclear. Note: Detected in the splicing complex carrying pre-mRNA
Alternative names
- crn-related protein kim1 antibody
- DKFZp762C1015 antibody
- HCNP antibody
see all
Database links
- Entrez Gene: 56949 Human
- Omim: 610850 Human
- SwissProt: Q9HCS7 Human
- Unigene: 9822 Human
References for Anti-XAB2 antibody (ab7289)
This product has been referenced in:
- Sugino Yet al. Septins as diagnostic markers for a subset of human asthenozoospermia. J Urol 180:2706-9 (2008).Read more (PubMed: 18951558) »
See 1 publication for this product
Publishing research using ab7289? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"