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Product Name
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XAGE1 peptide
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Product type
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Proteins and Peptides
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Peptide
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This peptide was used as an immunogen for ab21198 - XAGE1 antibody.
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Research areas
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Cancer >> Tumor immunology >> Tumor-associated antigens
Signal Transduction >> Protein Trafficking >> Nuclear Import / Export
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
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Relevance
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XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Sequence
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CPEAGEEQPQV (C-Terminus)
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this XAGE1 peptide is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to XAGE1
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