You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Related products

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

XBP1 protein (T7 Tag) (ab40096)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

XBP1 protein (T7 Tag)
See all XBP1 products (4) ...

Protein description

Recombinant full length protein (Human) fused to T7 tag at N-terminal end.

Expression host

E. coli

Properties

Purity

>95% by SDS-PAGE

Form

Liquid

Storage instructions

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.002% Sodium Azide
Constituents: 10mM Tris, Triton X-100, pH 8.0

Concentration

Concentration information loading...

Research areas

Epigenetics and Nuclear Signaling >> Transcription >> Transcription Factors
Epigenetics and Nuclear Signaling >> Transcription >> Other factors

  • SDS-PAGE - XBP1 protein (ab40096)SDS-PAGE - XBP1 protein (ab40096) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab40096 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

SDS-PAGE: Use at an assay dependent dilution.
Mass Spectrometry.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Protein info

Function

Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Involvement in disease

Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.

Sequence similarities

Belongs to the bZIP family.
Contains 1 bZIP domain.

Cellular localization

Nucleus.

Target information above from: UniProt accessionP17861 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

XBP1 protein (T7 Tag) images:

  SDS-PAGE - XBP1 protein (ab40096)

SDS-PAGE - XBP1 protein (ab40096)

Analysis of XBP1 recombinant protein (1µg) by SDS-PAGE. Coomassie blue staining.

References for XBP1 protein (T7 Tag) (ab40096)

ab40096 has not yet been referenced specifically in any publications.

Publishing research using ab40096? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"