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Products:Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Overview
Product name
Anti-XK antibody
See all XK products (2) ...
Description
Rabbit polyclonal to XK
Tested applications
IHC-P, ELISAmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Chimpanzee
Immunogen
Synthetic peptide: GK EDLQSSRDRD ETPS conjugated to KLH, corresponding to amino acids 409-425 of Human XK
GK EDLQSSRDRD ETPS
Epitope
Amino acids 409 to 425 of human XK
Positive control
Human adrenal and heart tissue
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Applications
Show applications key
Our Abpromise guarantee covers the use of ab64895 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use a concentration of 10 µg/ml
ELISA
ELISA: 1/1 - 1/1000.ELISA: 1/1 - 1/1000.
Target
Relevance
XK is the Kell blood group 'precursor substance'. This protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. The Kell blood group is constituted by two covalently linked antigens at the surface of red blood cells, Kell and KX. Whereas Kell is a metalloprotease with demonstrated in vitro enzymatic activity, the role of KX thereon, and/or alone, remains unknown, although its absence is linked to the McLeod syndrome, a neuroacanthocytosis. KX appears to be required for proper synthesis or presentation of the Kell antigens on the red blood cell surface.
Cellular localization
Membrane; Multi pass membrane protein
Alternative names
- Kell complex 37 kDa component antibody
- Membrane transport protein XK antibody
- XK related protein 1 antibody
see all
Database links
- Entrez Gene: 7504 Human
- Omim: 314850 Human
- SwissProt: P51811 Human
- Unigene: 78919 Human
Anti-XK antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - XK antibody (ab64895)
This image shows formalin fixed, paraffin embedded human adrenal tissue stained with ab64895 at 10µg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - XK antibody (ab64895)
This image shows formalin fixed, paraffin embedded human heart tissue stained with ab64895 at 10µg/ml.
References for Anti-XK antibody (ab64895)
ab64895 has not yet been referenced specifically in any publications.
Publishing research using ab64895? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"