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Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)
Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)
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Product Name 

XRCC2 antibody

 

See all XRCC2 antibodies (3)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to XRCC2

Immunogen 

Synthetic peptide derived from internal sequence of human XRCC2.

Reacts with 
(species key)

Hu

Specificity 

ab58466 detects endogenous levels of total XRCC2 protein.

Tested applications 
(see key)

ELISA, IHC-P


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: 1/10000.
IHC-P: 1/50 - 1/100.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

IHC-P: Human lung carcinoma tissue.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.

Relevance 

RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. There are five human homologues of RAD51; XRCC2, XRCC3, RAD51B, RAD51C, RAD51D, and they interact among themselves to form one big complex or several smaller complexes.

XRCC2 (X Ray Repair Cross Complementing 2), a component of the homologous recombination pathway, is essential for repairing the double strand DNA breaks by homologous recombination between sister chromatids.

 

XRCC2 antibody (ab58466)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

7516    (Human)

Omim

    

600375    (Human)

SwissProt

    

O43543    (Human)

Unigene

    

129727    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Purification notes 

The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this XRCC2 antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for XRCC2 antibody images, references, products related to ab58466 and other tools.

 

XRCC2 antibody images:

Product image  Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)

Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)

Ab58466, at 1/50 dilution, staining paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.

 
 

Search PubMed (MEDLINE) for references to XRCC2

 

XRCC2 antibody - more information

Customer reviews (feedback) regarding XRCC2 antibody

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Protocols for XRCC2 antibody

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