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Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)
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Product Name
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XRCC2 antibody
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See all XRCC2 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to XRCC2
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Immunogen
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Synthetic peptide derived from internal sequence of human XRCC2.
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Reacts with
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Hu
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Specificity
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ab58466 detects endogenous levels of total XRCC2 protein.
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Tested applications
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ELISA, IHC-P
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Abreviews
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Application notes
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Recommended dilutions
ELISA: 1/10000.
IHC-P: 1/50 - 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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IHC-P: Human lung carcinoma tissue.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.
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Relevance
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RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. There are five human homologues of RAD51; XRCC2, XRCC3, RAD51B, RAD51C, RAD51D, and they interact among themselves to form one big complex or several smaller complexes.
XRCC2 (X Ray Repair Cross Complementing 2), a component of the homologous recombination pathway, is essential for repairing the double strand DNA breaks by homologous recombination between sister chromatids.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Purification notes
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The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this XRCC2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for XRCC2 antibody images, references, products related to ab58466 and other tools.
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XRCC2 antibody images:
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 Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)
Ab58466, at 1/50 dilution, staining paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.
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Search PubMed (MEDLINE) for references to XRCC2
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XRCC2 antibody - more information
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Customer reviews (feedback) regarding XRCC2 antibody |
Customer FAQs regarding XRCC2 antibody |
Protocols for XRCC2 antibody |
Price and availability of products related to XRCC2 antibody |
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XRCC2 antibody - related products:
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XRCC2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about XRCC2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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