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Read our guarantee »Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.
Anti-XRCC2 antibody
See all XRCC2 products (5) ...
Rabbit polyclonal to XRCC2
ab58466 detects endogenous levels of total XRCC2 protein.
IHC-P, ELISAmore details
Reacts with
Human
Synthetic peptide derived from internal sequence of human XRCC2.
IHC-P: Human lung carcinoma tissue.
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Polyclonal
IgG
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.
Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)
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Our Abpromise guarantee covers the use of ab58466 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/50 - 1/100.
ELISA: 1/10000
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Belongs to the RecA family. RAD51 subfamily.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Nucleus.
Target information above from: UniProt accessionO43543
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Immunohistochemistry (Paraffin-embedded sections) - XRCC2 antibody (ab58466)

Ab58466, at 1/50 dilution, staining paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.
ab58466 has not yet been referenced specifically in any publications.
Publishing research using ab58466? Please let us know so that we can cite the reference in this datasheet
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