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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.
Overview
Product name
Anti-XRCC2 antibody, prediluted
See all XRCC2 products (5) ...
Description
Rabbit polyclonal to XRCC2, prediluted
Tested applications
IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide (Human) (N terminal). Unfortunately, the amino acid sequence is considered to be commercially sensitive.
Positive control
Testis
Properties
Form
Prediluted
Storage instructions
Store at +4°C. Do not freeze.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - XRCC2 antibody, prediluted (ab15253)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab15253 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
IHC-P
Application notes
IHC-P: 1/1. Perform enzymatic antigen retrieval before commencing with IHC staining protocol, by boiling tissue sections in 10mM
Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Sequence similarities
Belongs to the RecA family. RAD51 subfamily.
Post-translational
modifications
Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization
Nucleus.
Target information above from: UniProt accessionO43543
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- DNA repair protein XRCC2 antibody
- X ray repair complementing defective repair in Chinese hamster cells 2 antibody
- X ray repair cross complementing protein 2 antibody
see all
Database links
- Entrez Gene: 7516 Human
- Omim: 600375 Human
- SwissProt: O43543 Human
- Unigene: 647093 Human
Anti-XRCC2 antibody, prediluted images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - XRCC2 antibody, prediluted (ab15253)
ab15253 staining XRCC2 in Human testis by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
References for Anti-XRCC2 antibody, prediluted (ab15253)
ab15253 has not yet been referenced specifically in any publications.
Publishing research using ab15253? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"