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Product Name
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XRCC3 antibody
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See all XRCC3 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to XRCC3
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Immunogen
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Synthetic peptide (Human).
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Reacts with
(species key)
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Hu
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Specificity
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This antibody reacts with a 38 kD protein, known as XRCC3 (X-Ray Cross Complementing 3).
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Tested applications
(see key)
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IHC-Fr, IHC-P, IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method.
We suggest an incubation period of 30 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
WB: 1/100 - 1/250. Predicted molecular weight: 38 kDa.
IP: 1/100 - 1/250.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Testis.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Homologous Recomb.
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Relevance
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The XRCC3 gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. It is essential for repairing the double strand DNA breaks by homologous recombination between sister chromatids. It is homologous to RAD51. Five human homologues of RAD51; XRCC2, XRCC3, RAD51B, RAD51C, RAD51D, interact among themselves to form one big complex or several smaller complexes.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.05% Sodium Azide
Constituents: 1% BSA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this XRCC3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to XRCC3
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XRCC3 antibody - more information
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Customer reviews (feedback) regarding XRCC3 antibody |
Customer FAQs regarding XRCC3 antibody |
Protocols for XRCC3 antibody |
Price and availability of products related to XRCC3 antibody |
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XRCC3 antibody - related products:
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XRCC3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about XRCC3 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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