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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> Zinc Finger
Overview
Product name
Anti-YY1 antibody
See all YY1 products (9) ...
Description
Mouse monoclonal to YY1
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: VTMWSSDEKK DIDHETVVEE QIIGENSPPD YSEYMTGKKL PPGGIPGIDL SDPKQLAEFA RMKPRKIKED DAPRTIACPH KGCTKMFRDN SAMRKHLHTH , corresponding to amino acids 221-321 of Human YY1
VTMWSSDEKK DIDHETVVEE QIIGENSPPD YSEYMTGKKL PPGGIPGIDL SDPKQLAEFA RMKPRKIKED DAPRTIACPH KGCTKMFRDN SAMRKHLHTH
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Applications
Show applications key
Our Abpromise guarantee covers the use of ab58066 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. May play an important role in development and differentiation. The function of YY1 as an activator or a repressor is specified by the presence of other proteins. For example it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence.
Sequence similarities
Belongs to the YY transcription factor family.
Contains 4 C2H2-type zinc fingers.
Cellular localization
Nucleus matrix. Associated with the nuclear matrix.
Target information above from: UniProt accessionP25490
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- YY1 transcription factor antibody
- CF1 antibody
- Delta antibody
see all
Database links
- Entrez Gene: 7528 Human
- Omim: 600013 Human
- SwissProt: P25490 Human
- Unigene: 388927 Human
Anti-YY1 antibody images:
IHC-P - YY1 antibody (ab58066)
YY1 antibody (ab58066) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
Western blot - YY1 antibody (ab58066)
YY1 antibody (ab58066) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-YY1 antibody (ab58066)
ab58066 has not yet been referenced specifically in any publications.
Publishing research using ab58066? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"