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Anti-Yes1 antibody (ab61206)

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Overview

Product name

Anti-Yes1 antibody
See all Yes1 products (5) ...

Description

Mouse monoclonal to Yes1

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Recombinant full length protein with tag, corresponding to amino acids 1-544 of Human Yes1

Positive control

A431 whole cell lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Monoclonal

Isotype

IgG1

Research areas

Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Signal transducers
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Src Family

  • Western blot - Yes1 antibody (ab61206)Western blot - Yes1 antibody (ab61206) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab61206 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 - 5 µg/ml.Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).

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    ELISA

     ELISA: Use at an assay d...Read more →

    ELISA: Use at an assay dependent dilution.

Target

Function

Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.

Post-translational
modifications

Autophosphorylated.

Cellular localization

Cytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.

Target information above from: UniProt accessionP07947 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • c Yes antibody
  • Cellular Yes 1 protein antibody
  • Cellular Yes1 protein antibody
  • HsT441 antibody
  • P61 YES antibody
  • p61-Yes antibody
  • Proto oncogene tyrosine protein kinase YES antibody
  • Proto-oncogene c-Yes antibody
  • Tyrosine-protein kinase Yes antibody
  • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
  • Viral oncogene yes 1 homolog 1 antibody
  • Viral oncogene yes1 homolog 1 antibody
  • Yamaguchi sarcoma oncogene antibody
  • Yes 1 antibody
  • Yes antibody
  • YES_HUMAN antibody
  • YES1 antibody
see all

Database links

see all

Anti-Yes1 antibody images:

  Western blot - Yes1 antibody (ab61206)

Western blot - Yes1 antibody (ab61206)

Anti-Yes1 antibody (ab61206) at 1 µg/ml + A431 whole cell lysate at 50 µg/ml

Secondary
Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Predicted band size : 61 kDa
Observed band size : 61 kDa

References for Anti-Yes1 antibody (ab61206)

ab61206 has not yet been referenced specifically in any publications.

Publishing research using ab61206? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"