Z-ATAD-FMK, Caspase-12 inhibitor (ab141383)
Key features and details
- Caspase-12 inhibitor
- CAS Number:
- Purity: > 95%
- Soluble in DMSO to 20 mM
- Form / State: Lyophilized
- Source: Synthetic
Overview
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Product name
Z-ATAD-FMK, Caspase-12 inhibitor -
Description
Caspase-12 inhibitor -
Purity
> 95% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1152 ATAD-FMK, Z-,. 1152-5 is the same size as the 5 mg size of ab141383.
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Chemical structure
Properties
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Molecular weight
540.54 -
Molecular formula
C24H33N4O9F -
Sequence
ATAD (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK; Asp-4 = Asp(OMe)) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 20 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Associated products
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Related Products
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab141383 has been referenced in 2 publications.
- Han J et al. Myricetin activates the Caspase-3/GSDME pathway via ER stress induction of pyroptosis in lung cancer cells. Front Pharmacol 13:959938 (2022). PubMed: 36091790
- Wang J et al. Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission. Redox Biol 30:101415 (2020). PubMed: 31901590