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Product Name 

Z DNA binding protein antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to Z DNA binding protein

Immunogen 

Synthetic peptide corresponding to an 18 amino acid sequence from near the carboxy terminus of Human Z DNA binding protein.

Reacts with 
(species key)

Hu, Ms, Rat

Tested applications 
(see key)

ELISA, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Mouse small intestine tissue lysate.

Research areas 

Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA / Nucleotides

Relevance 

ZBP1 encodes a Z DNA binding protein. Z DNA formation is a dynamic process, largely controlled by the amount of supercoiling. ZBP1 may play a role in host defense against tumors and pathogens via sensing cytostolic DNA and activating the innate immune response.

 

Alternative names Z DNA binding protein antibody (ab81526)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

81030    (Human)
58203    (Mouse)
171091    (Rat)

Omim

    

606750    (Human)

SwissProt

    

Q9H171    (Human)
Q9QY24    (Mouse)
Q8VDA5    (Rat)

Unigene

    

302123    (Human)
116687    (Mouse)
67419    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: PBS

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified IgG prepared from whole serum by affinity chromatography.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Z DNA binding protein antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to Z DNA binding protein

 

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