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Z-VAD-FMK

Product code: ab120382 (formerly Asc-382)

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Overview

Product name

Z-VAD-FMK

Description

Irreversible general caspase inhibitor

Biological description

An irreversible general caspase inhibitor, useful for non-cellular in vitro  studies involving isolated, purified or recombinant caspase enzymes. Unlike Z-VAD (OMe)-FMK (ab120487), pretreatment with an esterase is not required.

Purity

> 98%

General notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Properties

Chemical name

N-Benzyloxycarbonyl-Val-Ala-Asp(O-Me)-fluoromethyl ketone

Molecular Weight

453.46

Chemical structure

Chemical Structure

Molecular formula

C21H28FN3O7

Solubility

Soluble in DMSO to 20 mM

Storage instructions

Store at -20°C (desiccating conditions).

Research areas

Biochemicals >> Research Area >> Stroke >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Respiratory disease >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Pain & inflammation >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Obesity >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Hypertension >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Heart disease >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Diabetes >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Cancer >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Research Area >> Alzheimer's Disease >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Pharmacology >> Signaling >> Apoptosis & cell cycle >> Caspase
Biochemicals >> Pharmacology >> Enzymes >> Caspase
Biochemicals >> Chemical Type >> Bioactive peptides

References for Z-VAD-FMK (ab120382)

This product has been referenced in:

See all 3 publications for this product

Publishing research using ab120382? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"