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Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - ZAP70 antibody (ab31009)
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Product Name
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ZAP70 antibody, prediluted
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See all ZAP70 antibodies (25)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ZAP70, prediluted
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Immunogen
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Synthetic peptide corresponding to C terminal of human ZAP70.
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Reacts with
(species key)
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Hu
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Tested applications
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IHC-P
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Abreviews
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Application notes
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Recommended dilutions
IHC-P: use neat for 30 min at room temperature. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. In particular, boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min and then cool at room temperature for 20 min.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Jurkat cells. Tonsil tissue.
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Cellular localization
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Cytoplasmic
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Research areas
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Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Other
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Immunology >> Adaptive Immunity >> T Cells >> CD
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Relevance
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ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP70 expression also defines a subset of Chronic Lymphocytic Leukemia (CLL) in patients with unmutated Ig gene and poor clinical course.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Prediluted
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ZAP70 antibody, prediluted is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ZAP70 antibody, prediluted images, references, products related to ab31009 and other tools.
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ZAP70 antibody, prediluted images:
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 Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - ZAP70 antibody (ab31009)
Immunohistochemical analysis of ZAP70 expression in paraffin embedded formalin fixed human tonsil tissue section, using neat ab31009.
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Search PubMed (MEDLINE) for references to ZAP70
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ZAP70 antibody, prediluted - more information
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ZAP70 antibody, prediluted - related products:
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ZAP70 antibody, prediluted - other tools:
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Contact Abcam with a Technical Enquiry about ZAP70 antibody, prediluted |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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