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Products:Cell Biology >> Cell Cycle >> Cell Division >> Other cell division antibodies
Overview
Product name
Anti-ZWILCH antibody
See all ZWILCH products (3) ...
Description
Mouse monoclonal to ZWILCH
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-478 of Human ZWILCH
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Cell Biology >> Cell Cycle >> Cell Division >> Other cell division antibodies
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Western blot - ZWILCH antibody (ab57533)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57533 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.
Sequence similarities
Belongs to the ZWILCH family.
Cellular localization
Chromosome > centromere > kinetochore.
Target information above from: UniProt accessionQ9H900
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- FLJ10036 antibody
- FLJ16343 antibody
- hZwilch antibody
see all
Database links
- Entrez Gene: 55055 Human
- Omim: 609984 Human
- SwissProt: Q8N404 Human
- SwissProt: Q9H900 Human
- Unigene: 21331 Human
Anti-ZWILCH antibody images:
Western blot - ZWILCH antibody (ab57533)
Western blot against tagged recombinant protein immunogen using ab57533 ZWILCH antibody at 1ug/ml. Predicted band size of immunogen is 79 kDa
References for Anti-ZWILCH antibody (ab57533)
ab57533 has not yet been referenced specifically in any publications.
Publishing research using ab57533? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"