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Products:Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Overview
Product name
Anti-Zhangfei antibody
See all Zhangfei products (3) ...
Description
Rabbit polyclonal to Zhangfei
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow
Immunogen
Synthetic peptide corresponding to a region within internal sequence amino acids 288-337 (GLRLTTSLFR DSPAGDHDYA LPVGKQKQDL LEEDDSAGGV CLHVDKDKVS) of human Zhangfei (NP_001034707).
GLRLTTSLFR DSPAGDHDYA LPVGKQKQDL LEEDDSAGGV CLHVDKDKVS
Positive control
Human fetal muscle lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
ab85468 is purified by a peptide affinity chromatography method.
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
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Western blot - Zhangfei antibody (ab85468)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab85468 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 µg/mlPredicted molecular weight: 37 kDa.
Target
Function
Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Tissue specificity
In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
Sequence similarities
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.
Cellular localization
Nucleus. Colocalizes at punctate nuclear structures with CREB3 and HCFC1.
Target information above from: UniProt accessionQ9NS37
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 6330417B10Rik antibody
- AI225749 antibody
- AI606244 antibody
see all
Database links
- Entrez Gene: 58487 Human
- Entrez Gene: 233490 Mouse
- Entrez Gene: 293112 Rat
- Omim: 606444 Human
- SwissProt: Q9NS37 Human
- SwissProt: Q91ZR3 Mouse
- Unigene: 535319 Human
- Unigene: 714910 Human
see all
Anti-Zhangfei antibody images:
Western blot - Zhangfei antibody (ab85468)
Anti-Zhangfei antibody (ab85468) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 37 kDa
Observed band size : 37 kDa
References for Anti-Zhangfei antibody (ab85468)
ab85468 has not yet been referenced specifically in any publications.
Publishing research using ab85468? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"