• Product name
  • Description
    Rabbit polyclonal to A1CF
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (ESNHKSGDGL SGTQKEAALR ALVQRTGYSL VQENGQRKYG GPPPGWDAAP) of Human A1CF (NP_055391).

  • Positive control
    • Human fetal spleen lysate



Our Abpromise guarantee covers the use of ab94598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 65 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function
    Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.
  • Tissue specificity
    Widely expressed with highest levels in brain, liver, pancreas, colon and spleen.
  • Sequence similarities
    Contains 3 RRM (RNA recognition motif) domains.
  • Domain
    The RRM domains are necessary but not sufficient for binding to APOB mRNA. Additional residues in the pre-RRM and C-terminal regions are required for RNA-binding and for complementing APOBEC1 activity.
  • Cellular localization
    Nucleus. Endoplasmic reticulum. Cytoplasm. Predominantly nuclear where it localizes to heterochromatin. Also cytoplasmic where it is found at the outer surface of the endoplasmic reticulum (By similarity). Shuttles between the nucleus and cytoplasm. May be transported into the nucleus by the nuclear import protein TNPO2/TRN2 or by APOBEC1.
  • Information by UniProt
  • Database links
  • Alternative names
    • A1CF antibody
    • A1CF_HUMAN antibody
    • ACF antibody
    • ACF64 antibody
    • ACF65 antibody
    • Apo B RNA editing protein antibody
    • Apobec 1 complementation factor antibody
    • Apobec 1 complementation factor (ACF) (ASP) antibody
    • APOBEC 1 stimulating protein antibody
    • APOBEC1 complementation factor antibody
    • APOBEC1 stimulating protein antibody
    • APOBEC1-stimulating protein antibody
    • APOBEC1CF antibody
    • ASP antibody
    • MGC163391 antibody
    • RP11-564C4.2 antibody
    see all

Anti-A1CF antibody images

  • Anti-A1CF antibody (ab94598) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 65 kDa

References for Anti-A1CF antibody (ab94598)

ab94598 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94598.
Please use the links above to contact us or submit feedback about this product.


Sign up