Overview

  • Product name
    A23187 (Calcimycin)
  • Description
    Ca2+ ionophore
  • Alternative names
    • calcimycin
  • Biological description
    A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against Gram-positive bacteria.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Boot JH & Van Hilten JA The use of the divalent calcium-ionophore A23187 as a biochemical tool in pharmacological and in vitro toxicological studies. Cell Struct Funct 21:97-9 (1996). Read more (PubMed: 8790938) »
  • Pressman BC Biological applications of ionophores. Annu Rev Biochem 45:501-30 (1976). Read more (PubMed: 786156) »
  • Pfeiffer DR  et al. Ultraviolet and fluorescent spectral properties of the divalent cation ionophore A23187 and its metal ion complexes. Biochemistry 13:4007-14 (1974). Read more (PubMed: 4416784) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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