Overview

  • Product nameAnti-A2ML1 antibody
  • Description
    Mouse polyclonal to A2ML1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-158 of Human A2ML1

  • Positive control
    • A2ML1 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab72872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 18 kDa.

Target

  • RelevanceA2ML1 is a new member of the alpha 2-macroglobulin protease inhibitor family, and shares most the characteristics of this family. It is the first family member detected in the epidermis and may play an important role during desquamation by inhibiting extracellular proteases. The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • A2ML 1 antibody
    • Alpha 2 macroglobulin like 1 antibody
    • Alpha 2 macroglobulin like protein 1 antibody
    • C3 and PZP like alpha 2 macroglobulin domain containing protein 9 antibody
    • CPAMD9 antibody
    • DKFZp686C1729 antibody
    • DKFZp686D2011 antibody
    • DKFZp686G1812 antibody
    • DKFZp686L1821 antibody
    • DKFZp686O1010 antibody
    • FLJ16045 antibody
    • FLJ25179 antibody
    • FLJ39129 antibody
    • FLJ41597 antibody
    • FLJ41598 antibody
    • FLJ41607 antibody
    see all

Anti-A2ML1 antibody images

  • All lanes : Anti-A2ML1 antibody (ab72872) at 1/500 dilution

    Lane 1 : A2ML1 transfected 293T cell lysate
    Lane 2 : non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 18 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

References for Anti-A2ML1 antibody (ab72872)

This product has been referenced in:
  • Burgener A  et al. A systems biology examination of the human female genital tract shows compartmentalization of immune factor expression. J Virol 87:5141-50 (2013). Human . Read more (PubMed: 23449785) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"